null

SMILES Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=S)c12

InChI Key InChIKey=GHMWCNIIKUZAOU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19956   

TargetEstrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nM EC50:  1.67E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2N82PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4CF5PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM19956(3-arylquinazolinethione, 1bd | 7-hydroxy-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 79nM EC50:  222nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2N82PubMed