null

SMILES Cc1ccc(cc1)N1CCc2cc(O)ccc2C1(C)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=GBFZZWRAKSCSNO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 20590   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 31nM EC50:  3.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 354nM EC50:  448nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 31.0nMAssay Description:Inhibition of binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 448nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 354nMAssay Description:Inhibition of binding to human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20590(1-methyl-2-(4-methylphenyl)-1-{4-[2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed