null

SMILES CC(C)c1ccc(cc1)N1CCc2cc(O)ccc2C1(C)c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=DKSQEJYZOQNOID-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 20597   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 71nM EC50:  5.20nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nM EC50:  4.78E+3nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of binding to human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 71.0nMAssay Description:Inhibition of binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20597(1-methyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed