null

SMILES CC1(N(CCc2cc(O)ccc12)c1cccc(O)c1)c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=COAUZXWBCIRBQG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 20598   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 31nM EC50:  0.600nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 190nM EC50:  33nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PQQPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of binding to human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 33.0nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of transcriptional activation by human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20598(2-(3-hydroxyphenyl)-1-methyl-1-{4-[2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 31.0nMAssay Description:Inhibition of binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4R5WPubMed