null

SMILES Cc1nc2cc(Cn3cc(cn3)C(=O)NCc3c(C)cc(N)nc3C)ccc2n1C

InChI Key InChIKey=ZGMRJKJEDUMBBI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212133   

TargetPlasma kallikrein(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM212133(US9290485, 165)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in â¿¿assay bufferâ¿¿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4G73US Patent