null

SMILES COc1ccc(F)c(F)c1CCNC(=S)Nc1ccc(Br)cn1

InChI Key InChIKey=YWRMGNFFDSLFNI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2138   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2138(1-(5-bromopyridin-2-yl)-3-[2-(2,3-difluoro-6-metho...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2138(1-(5-bromopyridin-2-yl)-3-[2-(2,3-difluoro-6-metho...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2138(1-(5-bromopyridin-2-yl)-3-[2-(2,3-difluoro-6-metho...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed