null

SMILES Brc1ccc(NC(=S)NCCc2c[nH]c3ccccc23)nc1

InChI Key InChIKey=GYXKZCBDZOVHQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 2151   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2151(1-(5-bromopyridin-2-yl)-3-[2-(1H-indol-3-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institute

Curated by ChEMBL
LigandPNGBDBM2151(1-(5-bromopyridin-2-yl)-3-[2-(1H-indol-3-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SX6CD8PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2151(1-(5-bromopyridin-2-yl)-3-[2-(1H-indol-3-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2151(1-(5-bromopyridin-2-yl)-3-[2-(1H-indol-3-yl)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed