null

SMILES Clc1ccc(NC(=S)NCCN2C(=O)c3ccccc3C2=O)nc1

InChI Key InChIKey=HDMIEYWFCFYJJE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2156   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2156(1-(5-chloropyridin-2-yl)-3-[2-(1,3-dioxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2156(1-(5-chloropyridin-2-yl)-3-[2-(1,3-dioxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Lilly Research Laboratories

LigandPNGBDBM2156(1-(5-chloropyridin-2-yl)-3-[2-(1,3-dioxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KSNPubMed