null

SMILES CCC1(C)SC(NC23CCC(CC2)C3)=NC1=O

InChI Key InChIKey=GJACSEPSTCDTAA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22462   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22462(2-Amino-1,3-thiazol-4(5H)-one, 5f | 2-{bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataKi:  73nM ΔG°:  -9.63kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22462(2-Amino-1,3-thiazol-4(5H)-one, 5f | 2-{bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed