null

SMILES O=C1N=C(NC2CCCCCCC2)SC11CCCC1

InChI Key InChIKey=JRXIMHQYNOCOAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22471   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22471(2-(cyclooctylamino)-1-thia-3-azaspiro[4.4]non-2-en...)copy SMILEScopy InChI
Affinity DataKi:  14nM ΔG°:  -10.6kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22471(2-(cyclooctylamino)-1-thia-3-azaspiro[4.4]non-2-en...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed