null

SMILES CNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl

InChI Key InChIKey=XZRBUFDWBARYKU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22972   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0247PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0247PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed