null

SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NOCc2ccccc2)c1Cl

InChI Key InChIKey=NTVDNFZZUDOSTQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22976   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22976(CHEMBL358222 | Meclofenamic acid derivative, 28 | ...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22976(CHEMBL358222 | Meclofenamic acid derivative, 28 | ...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0247PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22976(CHEMBL358222 | Meclofenamic acid derivative, 28 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0247PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22976(CHEMBL358222 | Meclofenamic acid derivative, 28 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed