null

SMILES Cc1c(cc(n1CC(F)(F)CN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=ZIHIAFOGWPAXRL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230278   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230278(US9340500, I-122)copy SMILEScopy InChI
Affinity DataKi:  240nM ΔG°:  -9.39kcal/mole IC50: 780nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent