null

SMILES COc1ccc(CNC(=O)c2cc(=O)c3c(O)cc(OCCc4ccc(NC(=O)C(O)=O)c(OC)c4)cc3o2)cc1

InChI Key InChIKey=MLDHFNNJFGENAK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 23229   

TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6HCVPubMed
TargetL-lactate dehydrogenase B chain(Bos taurus (bovine))
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6HCVPubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 2.66E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6HCVPubMed
TargetMalate dehydrogenase, cytoplasmic(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 6.78E+3nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged MDH-1 (3 to 334) expressed in Escherichia coli using oxaloacetic acid as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6ZTTPubMed
TargetMalate dehydrogenase, cytoplasmic(Sus scrofa (pig))
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6HCVPubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged MDH-2 (20 to 338) expressed in Escherichia coli using oxaloacetic acid as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6ZTTPubMed
TargetMalate dehydrogenase, mitochondrial(Sus scrofa (pig))
University of Mississippi

LigandPNGBDBM23229(Oxamic acid derivative, 7 | [(4-{2-[(5-hydroxy-2-{...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6HCVPubMed