null

SMILES CC(C)Sc1sc(C(O)=O)c(c1C#N)-c1cccc(Cl)c1

InChI Key InChIKey=MEXYZCOKYUVLHX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238354   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Centre de Recherche de Gif

LigandPNGBDBM238354(3-(3-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.5Assay Description:Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on Wallac Victor fluorimeter from Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238354(3-(3-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
LigandPNGBDBM238354(3-(3-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Assays were realized on 96-well plates, as described for yeast FTase but octyl-D-glucopyranoside (0.18%) was used instead of CHAPS and the solution c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed