null

SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCc2c[nH]nn2)c1

InChI Key InChIKey=QUGNOBIRXQGNST-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 241108   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M2GUS Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB84DVPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB84DVPubMed
TargetAtaxin-2(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM241108(US9409895, 19 | US9630945, 19)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4Z5RUS Patent