null
SMILES O=C1CCCN1C1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1
InChI Key InChIKey=OAUXHFPOFOZZLZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 24220
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataIC50: 2.70E+3nMT: 2°CAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Janssen Research& Development, LLC
Curated by ChEMBL
Janssen Research& Development, LLC
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Janssen Research& Development, LLC
Curated by ChEMBL
Janssen Research& Development, LLC
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Inhibition of LTA4H in human whole blood assessed as decrease in LTB4 productionMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Janssen Research& Development, LLC
Curated by ChEMBL
Janssen Research& Development, LLC
Curated by ChEMBL
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair