null

SMILES CCNC(=O)Nc1nc2cc(cc(OCc3ccccc3)c2[nH]1)-c1cccnc1

InChI Key InChIKey=VMFOCQGPXUINDE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24612   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Vertex

LigandPNGBDBM24612(1-[7-(benzyloxy)-5-(pyridin-3-yl)-1H-1,3-benzodiaz...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F7TPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Vertex

LigandPNGBDBM24612(1-[7-(benzyloxy)-5-(pyridin-3-yl)-1H-1,3-benzodiaz...)copy SMILEScopy InChI
Affinity DataKi:  35nM ΔG°:  -10.3kcal/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F7TPubMed
TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Vertex

LigandPNGBDBM24612(1-[7-(benzyloxy)-5-(pyridin-3-yl)-1H-1,3-benzodiaz...)copy SMILEScopy InChI
Affinity DataKi:  390nMAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F7TPubMed