null

SMILES CCNC(=O)c1ccc(s1)C(=O)C(F)(F)F

InChI Key InChIKey=XYMSMXPTPHUKFO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 25155   

TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25155(CHEMBL462146 | N-ethyl-5-(2,2,2-trifluoroacetyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 310nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed