null

SMILES C[C@@H](NC(=O)c1ccc(s1)C(=O)C(F)(F)F)c1ccccc1

InChI Key InChIKey=DPKHRWMGXRDLLO-SECBINFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 25158   

TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 320nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 230nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 160nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 76nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25158(CHEMBL507716 | N-[(1R)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 360nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed