null

SMILES C[C@H](NC(=O)c1ccc(s1)C(=O)C(F)(F)F)c1ccccc1

InChI Key InChIKey=DPKHRWMGXRDLLO-VIFPVBQESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 25159   

TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 280nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 170nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 210nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC6 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987XHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC1 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987XHPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HDAC3 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987XHPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed