null

SMILES C[C@@H](NC(=O)c1ccc(s1)C(=O)NO)c1ccccc1

InChI Key InChIKey=BOZZDVHKSLWIQS-SECBINFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 25168   

TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25168(2-N-hydroxy-5-N-[(1R)-1-phenylethyl]thiophene-2,5-...)copy SMILEScopy InChI
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25168(2-N-hydroxy-5-N-[(1R)-1-phenylethyl]thiophene-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25168(2-N-hydroxy-5-N-[(1R)-1-phenylethyl]thiophene-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25168(2-N-hydroxy-5-N-[(1R)-1-phenylethyl]thiophene-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25168(2-N-hydroxy-5-N-[(1R)-1-phenylethyl]thiophene-2,5-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed