null

SMILES FC(F)C(=O)c1ccc(s1)C(=O)N1CCc2ccccc12

InChI Key InChIKey=WZGNPOPOCGTSMZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 25172   

TargetHistone deacetylase 6(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)copy SMILEScopy InChI
Affinity DataIC50: 420nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)copy SMILEScopy InChI
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed