null

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC1COCCN(C)CCOC1

InChI Key InChIKey=VRPYTXIQAZYPAK-URLMMPGGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25376   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Purdue Research Foundation

US Patent
LigandPNGBDBM25376((R)-(hydroxyethylamino)sulfonamide isostere, 3m | ...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Enzyme inhibitory assay utilizes a protocol described by Toth and Marshall (Toth, M. V.; Marshall G.R. A simple, continuous fluormetric assay for HIV...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9VZHUS Patent
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM25376((R)-(hydroxyethylamino)sulfonamide isostere, 3m | ...)copy SMILEScopy InChI
Affinity DataKi:  19nM ΔG°:  -10.5kcal/mole IC50: 1.00E+3nMpH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G15Z51PubMed