null

SMILES Cc1c2B(O)OCc2ccc1Oc1cccc(CN)c1F

InChI Key InChIKey=XEZNMDMVOXPEQL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 258600   

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 247nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 216nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.19nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 3.38nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent