null

SMILES Cc1cnc2c(NCCN)nc3cc(sc3n12)-c1ccc[nH]1

InChI Key InChIKey=DDOFIMMBCNWUIK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25933   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM25933(N-(2-aminoethyl)-12-methyl-4-(1H-pyrrol-2-yl)-3-th...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8R50PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM25933(N-(2-aminoethyl)-12-methyl-4-(1H-pyrrol-2-yl)-3-th...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SHGPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM25933(N-(2-aminoethyl)-12-methyl-4-(1H-pyrrol-2-yl)-3-th...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8R50PubMed