null

SMILES CNC(=O)c1cc(Oc2ccc3n(C)c(Nc4ccc(Cl)c(c4)C(F)(F)F)nc3c2)ccn1

InChI Key InChIKey=MCKKYADDOIQSEO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26020   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Novartis

LigandPNGBDBM26020(4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl](methyl...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56H1CPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

LigandPNGBDBM26020(4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl](methyl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.8 T: 2°CAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56H1CPubMed