null

SMILES COc1cncc(c1)-c1cc2c(CN(C(=O)C22CC2)c2c(F)c(OC)cc(OC)c2F)cn1

InChI Key InChIKey=GMYCPVQQFIVFGR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 261904   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:In the FGFR Enzymatic Assay after dilution in assay buffer, added to the plate and pre-incubated for 5 to 10 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In the FGFR Enzymatic Assay after dilution in assay buffer, added to the plate and pre-incubated for 5 to 10 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In the FGFR Enzymatic Assay after dilution in assay buffer, added to the plate and pre-incubated for 5 to 10 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In the FGFR Enzymatic Assay after dilution in assay buffer, added to the plate and pre-incubated for 5 to 10 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC9298US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73HS1US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M97QSUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Corporation

US Patent
LigandPNGBDBM261904(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:FGFR1, FGFR2, and FGFR4 are measured under equivalent conditions with the following changes in enzyme and ATP concentrations: FGFR1, 0.02 nM and 210 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3HD3US Patent