null

SMILES Oc1ccc(cc1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2cc(O)ccc2CCC1

InChI Key InChIKey=BOUYTPSKRGKAOB-MHZLTWQESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 263664   

TargetEstrogen receptor(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263664(US9714221, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent
TargetEstrogen receptor(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263664(US9714221, Example 1)copy SMILEScopy InChI
Affinity DataEC50:  0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 4 hrs by Alexafluor-488 conjugate anti-rabbit antibody/Syto-64 staining based immu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MB3PubMed
TargetEstrogen receptor [Y537S](Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263664(US9714221, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent
TargetEstrogen receptor [D538G](Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263664(US9714221, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent