null
SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1C(=O)Nc1cncnc1
InChI Key InChIKey=MDBBPOZQZACUGK-UHFFFAOYSA-N
PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 26373
Affinity DataIC50: 239nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair