null

SMILES CC1(C)Cc2cc(ccc2N1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(cc2CCC1)C(O)=O

InChI Key InChIKey=XGPVTAWGBZBRSK-LJAQVGFWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263847   

TargetEstrogen receptor(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263847(6-(2,2-dimethylindolin-5-yl)-5-[4-[(3S)-1-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent
TargetEstrogen receptor [Y537S](Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263847(6-(2,2-dimethylindolin-5-yl)-5-[4-[(3S)-1-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent
TargetEstrogen receptor [D538G](Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM263847(6-(2,2-dimethylindolin-5-yl)-5-[4-[(3S)-1-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N58PB1US Patent