null

SMILES Nc1nccn2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@H]1CN(CCO1)C1COC1

InChI Key InChIKey=GXCALHHQCMVHBO-LJQANCHMSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267934   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V.

US Patent
LigandPNGBDBM267934(4-{8-amino-3-[(2R,5S)-4-ethyl-5-(hydroxymethyl)mor...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H9977TUS Patent