null

SMILES CC1(N=C(N(C[C@@H]2CCN(C2)C(=O)C2CC2)C1=O)c1ccc(cc1)-c1ccc2occc2c1)c1ccccc1

InChI Key InChIKey=VEDSEHJIDLELRZ-LWMFVPLKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 268738   

TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM268738((4RS)-2-(4-(Benzofuran-5-yl)phenyl)-1-(((R)-1-(cyc...)copy SMILEScopy InChI
Affinity DataIC50: 155nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM268738((4RS)-2-(4-(Benzofuran-5-yl)phenyl)-1-(((R)-1-(cyc...)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H134CBUS Patent
Target1,5-anhydro-D-fructose reductase(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM268738((4RS)-2-(4-(Benzofuran-5-yl)phenyl)-1-(((R)-1-(cyc...)copy SMILEScopy InChI
Affinity DataIC50: 537nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent