null

SMILES CNC(=O)c1ccc(cc1F)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(cc1)C#N

InChI Key InChIKey=JRYTXSJOBAOEPP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 283255   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ70TMUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70HV3US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ686NUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4SR7US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66P3NUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF01G7US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:To analyze LSD1 inhibitor efficacy in cells, a CD11b flow cytometry assay was performed. LSD1 inhibition induces CD11b expression in THP-1 (AML) cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5HRTUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X63QBCUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29889CVUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS5ZGPUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5XFHUS Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
CELGENE QUANTICEL RESEARCH, INC.

US Patent
LigandPNGBDBM283255(US10023543, Example 40 | US10207999, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5HRTUS Patent