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SMILES CC(C)(C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=GAVZPZUJCRTQNY-LLVKDONJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28953   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research

LigandBDBM28953((2S)-N-(4-chlorophenyl)-1-hydroxy-3,3-dimethylbuta...)copy SMILEScopy InChI

Affinity DataEC50:  2.91E+4nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VJMPubMed