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SMILES CC[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=DAFCUKNGSQFVAC-BXKDBHETSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28955   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research

LigandBDBM28955((2S,3R)-N-(4-chlorophenyl)-1-hydroxy-3-methylpenta...)copy SMILEScopy InChI

Affinity DataEC50:  758nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VJMPubMed