null

SMILES COC(=O)Nc1ccc(cc1)C(=O)N[C@@H](CCNC(=O)C1CCC1)C(=O)N1CCC[C@@]2(C1)OC(=O)Nc1ccc(Cl)cc21

InChI Key InChIKey=JCQSXOIXTAFCCK-NGQVCNFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289799   

TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM289799(Methyl (4-(((S)-1-((R)-6-chloro-2-oxo-1,2-dihydros...)copy SMILEScopy InChI
Affinity DataKi:  50.7nM ΔG°:  -9.94kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR2197US Patent