null

SMILES Oc1ccc2ccccc2c1Cc1c([nH]c(=S)[nH]c1=O)-c1ccc(Br)cc1

InChI Key InChIKey=HWHNRRGQEQLDQM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29042   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of St Andrews

LigandPNGBDBM29042(cambinol analog, 6b)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8C6TPubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of St Andrews

LigandPNGBDBM29042(cambinol analog, 6b)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B28PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of St Andrews

LigandPNGBDBM29042(cambinol analog, 6b)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8C6TPubMed