null

SMILES Nc1ncnc2n(nc(C(=O)Nc3nc4ccccc4o3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=WUMMDJMYFAWMBN-GFCCVEGCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 291282   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TAIHO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291282(US10280174, Compound A | US9580432, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 0.813nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0WZRUS Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis

LigandPNGBDBM291282(US10280174, Compound A | US9580432, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 16.9nMAssay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against EGFR kinase activity in vitro, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q20K3US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TAIHO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291282(US10280174, Compound A | US9580432, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 1.19nMAssay Description:In a condition set for a method of measuring inhibitory activity in vitro of the compounds against BTK kinase activity, FL-Peptide 2 was used as a su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q20K3US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis

LigandPNGBDBM291282(US10280174, Compound A | US9580432, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 28.8nMpH: 7.5 T: 2°CAssay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against EGFR kinase activity in vitro, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0WZRUS Patent