null

SMILES C(N1CCOCC1)c1cnc2oc3c(nc(nc3c2c1)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=FQDZEXAWGGTCSJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 291363   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 355nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38VM2US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38VM2US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38VM2US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Lek Pharmaceuticals d.d.

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Please see articleMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5H9PUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 355nMAssay Description:Please see articleMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5H9PUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Please see articleMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5H9PUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Karus Therapeutics Limited

US Patent
LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Please see articleMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5H9PUS Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Lek Pharmaceuticals d.d.

LigandPNGBDBM291363(2-(1H-Indol-4-yl)-4-morpholin-4-yl-8-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:PI3K Isoform using biochemical assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38VM2US Patent