null
SMILES O=C(\C=C\c1ccccc1)c1ccccc1
InChI Key InChIKey=DQFBYFPFKXHELB-VAWYXSNFSA-N
PDB links: 4 PDB IDs contain inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 29143
Affinity DataKi: 56nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI cells assessed as inhibition of H2O2 production using kynuramine as subst...More data for this Ligand-Target Pair
Affinity DataKi: 1.46E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI cells assessed as inhibition of H2O2 production using kynuramine as subst...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using soluble starch as substrate after 30 mins by Bernfeld methodMore data for this Ligand-Target Pair
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.25E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+5nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMT: 2°CAssay Description:Binding of chalcone 4 and chlcone 1 to CSCL12 was examined by monitoring changes in the emission intensity of intrinsic Trp fluorescence of the chemo...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
AtheroGenics, Inc.
Curated by ChEMBL
AtheroGenics, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of TNF-alpha-induced VCAM-1 expressionMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibitory activity against murine lipoxygenase-2.More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibitory activity against murine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 4.64E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+6nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.44E+4nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.19E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of human rhodamine-labelled soluble CD69 by standard plate inhibition assayMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.41E+3nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair