null

SMILES COc1ccc(F)cc1CCCC1CCC(CCN)O1

InChI Key InChIKey=KFFYQORCJDVDTB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 30132   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.10nM ΔG°:  -12.1kcal/mole EC50:  2.30nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6B7MPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  7.31E+3nM ΔG°:  -6.93kcal/mole EC50:  1.70E+4nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6B7MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  7.31E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nM EC50:  1.93E+3nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6B7MPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM30132(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GV0PubMed