null

SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccccc1

InChI Key InChIKey=NNQMSHWOTYMSDC-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 30178   

TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 7.5 T: 2°CAssay Description:The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))
Pfizer

LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetRibosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Pfizer

LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+5nMAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Pfizer

LigandPNGBDBM30178(Pyrrolopyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2794313PubMed