null

SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(C)n1

InChI Key InChIKey=HINOQCZIDBNXEI-FQEVSTJZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 311208   

TargetAP2-associated protein kinase 1(Mus musculus)TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataKi:  0.290nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetMyosin light chain kinase 2, skeletal/cardiac muscle(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QWSUS Patent

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5XCXUS Patent

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60S4PUS Patent

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9T6JUS Patent

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 3A4(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 1A2(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 2C19(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 2C9(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 2D6(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 3A4(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCytochrome P450 2B6(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 5.90E+3nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 540nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetBMP-2-inducible protein kinase(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 90nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetDeath-associated protein kinase 1(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetCyclin-G-associated kinase(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 210nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 190nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191S4US Patent

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent

LigandBDBM311208((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI

Affinity DataIC50: 1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930WGGUS Patent