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SMILES C[C@H]1CN(c2ccc(Cl)cc2)c2ccccc2-c2c(C)nnn12

InChI Key InChIKey=ZZJIAOWVSKZQGQ-LBPRGKRZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 313778   

TargetBromodomain-containing protein 2 [91-163](Homo sapiens (Human))
Catalyst Therapeutics Pty Ltd.

US Patent
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HFSUS Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
Catalyst Therapeutics Pty Ltd.

US Patent
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HFSUS Patent
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
Catalyst Therapeutics Pty Ltd.

US Patent
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HFSUS Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Catalyst Therapeutics Pty Ltd.

US Patent
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HFSUS Patent
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human His-tagged Brd3 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human His-tagged Brd2 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ13K2PubMed
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Catalyst Therapeutics Pty Ltd.

US Patent
LigandPNGBDBM313778(US10167292, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HFSUS Patent