null

SMILES Cn1cc(c(n1)-c1ccc(OCc2cnc3ccccc3n2)cc1)-c1ccncc1

InChI Key InChIKey=ZMKCAJWGTIMPTC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31604   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM31604(methyl substituted pyrazole, 25)copy SMILEScopy InChI

Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Pfizer

LigandBDBM31604(methyl substituted pyrazole, 25)copy SMILEScopy InChI

Affinity DataIC50: 5.09nMpH: 7.5 T: 2°CAssay Description:PDE activity was measured using a plate-based Scintillation Proximity Assay (SPA). For competitive enzyme inhibition assays, the substrate [3H]cAMP c...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q290223BPubMed