null

SMILES OC(CC1c2cncn2-c2ccccc12)C1CCCCC1

InChI Key InChIKey=MENMLCRHDMAGQE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 317215   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

US Patent
LigandPNGBDBM317215(US9617272, Compound 70 | US9981973, Compound 70)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7XQNUS Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
NewLink Genetics Corporation

US Patent
LigandPNGBDBM317215(US9617272, Compound 70 | US9981973, Compound 70)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7XQNUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

US Patent
LigandPNGBDBM317215(US9617272, Compound 70 | US9981973, Compound 70)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human IDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7D3XPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

US Patent
LigandPNGBDBM317215(US9617272, Compound 70 | US9981973, Compound 70)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35X00US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
NewLink Genetics Corporation

US Patent
LigandPNGBDBM317215(US9617272, Compound 70 | US9981973, Compound 70)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35X00US Patent