null

SMILES Cc1ccc2NC(C3CC=CC3c2c1)C(O)=O

InChI Key InChIKey=QYUJXIHOGIEIGB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 31758   

TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMpH: 7.0 T: 2°CAssay Description:Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N87841PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61HQ8PCBioAssay
TargetHeat shock 70 kDa protein 1A(Homo sapiens (Human))
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 4.77E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75DRWPCBioAssay
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
Sanford-Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 7.07E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289148TPCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in 25 mM DTT has been developed to assess actives that were identified in the Cdc25B HTS ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K48M5PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.98E+3nMAssay Description:The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3HWFPCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.85E+3nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2MCPPCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 7.35E+3nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Catalase has been developed to assess actives that were identified in the Cdc25B HTS A...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928QKPCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+4nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in 25 mM DTT with Catalase has been developed to assess actives that were identified in t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1J08PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Beta-Mercaptoethanol (BME) has been developed to assess actives that were identified i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0S8JPCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.89E+3nMAssay Description:The Cdc25B Phosphatase probe assessment dose response assay in Glutathione (GSH) has been developed to assess actives that were identified in the Cdc...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101KZPCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DB806HPCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K77GSPCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 6.26E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474894PCBioAssay
TargetEukaryotic translation initiation factor 4 gamma 1(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.44E+3nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN3686PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X8539PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4GWXPCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66J6BPCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7DPXPCBioAssay