null

SMILES OC(=O)CCN1CCC2(COc3cc(ccc23)C#Cc2ccccc2)CC1

InChI Key InChIKey=OWHUUJZBNSHXSC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 321336   

TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50:  25.1nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K7C5DUS Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: <3.16E+4nMAssay Description:The CHO-K1-human-S1P1-Aeqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K7C5DUS Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K7C5DUS Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as increase in calcium flux by aequorin-derived luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87DCTPubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:The CHO-human-S1P3-Aeqorin assay (CHO/Gal6/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (acces...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FC5US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50:  40nMAssay Description:Agonist activity at human S1P5 receptor expressed in CHO cells assessed as increase in calcium flux by aequorin-derived luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87DCTPubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50:  25.1nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FC5US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: >3.16E+4nMAssay Description:The CHO-K1-human-S1P1-Aeqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92FC5US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
AbbVie B.V.; AbbVie, Inc.

US Patent
LigandPNGBDBM321336(US10179791, Compound 303 | US10807991, Compound 30...)copy SMILEScopy InChI
Affinity DataEC50: <3.16E+4nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells assessed as increase in calcium flux by aequorin-derived luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87DCTPubMed