null

SMILES Cc1nnn(Cc2cc(Cl)ccc2\C=C\C(=O)N2CCN(Cc3coc(C)n3)CC2)n1

InChI Key InChIKey=SSUQKWCRLANIRC-GQCTYLIASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 322046   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM322046((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RN39XZUS Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM322046((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant ATX expressed in HEK293 cells assessed as inhibition of choline release using LPC (18:1) as substrate preincubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P13NNPubMed
LigandPNGBDBM322046((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P13NNPubMed
TargetAtaxin-1(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM322046((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W0DUS Patent